Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816019 | 0.80 | KMT2A (0.45) | RAB9AHDAC1TP53NR1I2PPARG | |
| SCHEMBL7938865 | 0.76 | LMNA (0.64) | RAB9AKDM4ETP53NPC1TDP1 | |
| SCHEMBL6819272 | 0.75 | LMNA (0.53) | RAB9AKDM4EKLK7TP53NPC1 | |
| SCHEMBL7946513 | 0.75 | PTPN1 (0.54) | RAB9AHDAC1NPC1TDP1MEN1 | |
| SCHEMBL6812039 | 0.74 | LMNA (0.46) | RAB9AHDAC1KDM4EKLK7TP53 | |
| SCHEMBL7939069 | 0.73 | LMNA (0.50) | RAB9AKDM4ETP53NPC1TDP1 | |
| SCHEMBL7950507 | 0.72 | KMT2A (0.56) | RAB9AKDM4ETP53NPC1MEN1 | |
| SCHEMBL7782993 | 0.71 | KMT2A (0.63) | RAB9ATP53NPC1MEN1KMT2A | |
| SCHEMBL6819664 | 0.71 | KCNB1 (0.39) | RAB9ANPC1CTDSP1TDP1MEN1 | |
| SCHEMBL6815153 | 0.71 | KMT2A (0.43) | RAB9AMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-B1 | THIOUREA INHIBITORS OF HERPES VIRUSES | WYETH CORP (US) | 2004-07-28 | — | — | EP | claimed |