Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GRK2 | P25098 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816867 | 0.91 | ALDH1A1 (0.59) | ALDH1A1MAPTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL6813393 | 0.91 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL6812824 | 0.90 | GAA (0.61) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL6817046 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBHPGDGRK2 | |
| SCHEMBL6817047 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBHPGDGRK2 | |
| SCHEMBL6815926 | 0.87 | GAA (0.58) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL6544904 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBHPGDGRK2 | |
| SCHEMBL6544900 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBHPGDGRK2 | |
| SCHEMBL6816832 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL3251942 | 0.82 | MAPT (0.49) | ALDH1A1MAPTPOLBGRK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140799-B1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | claimed |
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | claimed |
| EP-1140799-A1 | NOVEL PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | claimed |
| WO-2000041998-A1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | claimed |
| EP-1140799-B1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | disclosed |
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | disclosed |
| EP-1140799-A1 | NOVEL PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000041998-A1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | disclosed |