⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19311494 | 0.83 | — | — | |
| SCHEMBL28856371 | 0.83 | PKM (0.33) | — | |
| Carbamic Acid SCHEMBL25294163 | 0.78 | FFAR3 (0.38) | — | |
| SCHEMBL756617 | 0.75 | — | — | |
| SCHEMBL14886536 | 0.75 | — | — | |
| SCHEMBL335112 | 0.73 | — | — | |
| SCHEMBL11928221 | 0.72 | — | — | |
| SCHEMBL26111678 | 0.72 | — | — | |
| SCHEMBL25294161 | 0.72 | NQO1 (0.32) | — | |
| SCHEMBL1871799 | 0.72 | PKM (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074386-A1 | NOVEL AMINO PYRIMIDINE DERIVATIVES | Novartis AG (CH) | 2016-10-05 | — | — | EP | claimed |
| WO-2015079417-A1 | NOVEL AMINO PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2015-06-04 | — | — | WO | claimed |
| EP-4125846-A1 | PYRAZOLYLPROPANAMIDE COMPOUNDS AND USES THEREOF FOR TREATMENT OF PROSTATE CANCER | University of Tennessee Research Foundation (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-110062753-A | Antiviral compounds | 哈普洛根有限责任公司 | 2019-07-26 | — | — | CN | disclosed |
| US-9834518-B2 | Compounds for inhibiting cell proliferation in EGFR-driven cancers | ARIAD PHARMACEUTICALS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| EP-3074386-A1 | NOVEL AMINO PYRIMIDINE DERIVATIVES | Novartis AG (CH) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015079417-A1 | NOVEL AMINO PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2015-06-04 | — | — | WO | disclosed |
| US-20120316135-A1 | Compounds for Inhibiting Cell Proliferation in EGFR-Driven Cancers | ARIAD PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | US | disclosed |
| WO-2004039791-A1 | A PROCESS FOR THE PRODUCTION OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-2,3-EPOXY-2-METHYLPROPANAMIDE | INSTYTUT FARMACEUTYCZNY (PL) | 2004-05-13 | — | — | WO | disclosed |
| US-6515081-B2 | Thermosetting resin, compound containing one functional group which can react with thermosetting resin or its curing agent; sports applications, aerospace applications, industrial applications | TORAY INDUSTRIES, INC. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-6399199-B1 | EPOXY RESIN, CURING AGENT AND MATRIX RESIN | TORAY INDUSTRIES INC. (JP) | 2002-06-04 | — | — | US | disclosed |
| US-20020007022-A1 | EPOXY RESIN COMPOSITION FOR FIBER-REINFORCED COMPOSITE MATERIAL, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL | TORAY INDUSTRIES, INC. (JP) | 2002-01-17 | — | — | US | disclosed |
| EP-0947562-A1 | EPOXY RESIN COMPOSITION FOR FIBER-REINFORCED COMPOSITE MATERIAL, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL | TORAY INDUSTRIES, INC. (JP) | 1999-10-06 | — | — | EP | disclosed |