Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.51 |
| ▸ | PPARA | Q07869 | 19/20 | 0.51 |
| ▸ | PPARD | Q03181 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816032 | 0.91 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL13721668 | 0.82 | KDM4E (0.60) | PPARGPPARAPPARD | |
| SCHEMBL9755734 | 0.81 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL6815602 | 0.81 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL12617845 | 0.79 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL6817219 | 0.79 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL6181318 | 0.79 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL6815608 | 0.77 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL6815601 | 0.77 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL6815603 | 0.77 | PPARG (0.50) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011446-A1 | INDANE, DIHYDROBENZOFURAN, AND TETRAHYDRONAPHTHALENE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |