Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.50 |
| ▸ | PPARA | Q07869 | 18/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817219 | 0.86 | PPARG (0.53) | PPARGPPARAPPARDPTPN2PTPN1 | |
| SCHEMBL6815608 | 0.84 | PPARG (0.50) | PPARGPPARAPPARDPTPN2PTPN1 | |
| SCHEMBL6815601 | 0.84 | PPARG (0.50) | PPARGPPARAPPARDPTPN2PTPN1 | |
| SCHEMBL8888613 | 0.82 | FDPS (0.64) | PPARGPPARAPPARD | |
| SCHEMBL8888616 | 0.82 | FDPS (0.64) | PPARGPPARAPPARD | |
| SCHEMBL6817025 | 0.81 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL6967143 | 0.79 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL6967147 | 0.79 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL6183000 | 0.79 | PPARG (0.58) | PPARGPPARAPPARDPTPN2PTPN1 | |
| SCHEMBL6183006 | 0.79 | PPARG (0.58) | PPARGPPARAPPARDPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011446-A1 | INDANE, DIHYDROBENZOFURAN, AND TETRAHYDRONAPHTHALENE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |