SCHEMBL6817030

SCHEMBL6817030

c1ccc(N(c2ccc(Nc3ccc(N(c4ccccc4)c4cccc5ccccc45)cc3)cc2)c2cccc3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.46
ALDH1A1 P00352 4/20 0.46
ALOX15 P16050 2/20 0.46
TSHR P16473 2/20 0.46
CYP3A4 P08684 2/20 0.46
HPGD P15428 2/20 0.46
TP53 P04637 1/20 0.46
CDC25B P30305 1/20 0.46
ATM Q13315 1/20 0.46
SIGMAR1 Q99720 5/20 0.43
KDM1A O60341 5/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
ALOX12 P18054 1/20 0.40
PTGS1 P23219 1/20 0.40
SLC6A2 P23975 1/20 0.40
MAPK1 P28482 1/20 0.40
PTGS2 P35354 1/20 0.40
HTR2B P41595 1/20 0.40
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18055092 1.00 HSD17B10 (0.46) HSD17B10ALDH1A1ALOX15TSHRCYP3A4
SCHEMBL1034193 0.98 ALDH1A1 (0.49) HSD17B10ALDH1A1ALOX15TSHRCYP3A4
SCHEMBL12700539 0.98 ALDH1A1 (0.44) HSD17B10ALDH1A1ALOX15TSHRCYP3A4
SCHEMBL13190705 0.97 ALDH1A1 (0.47) HSD17B10ALDH1A1ALOX15TSHRCYP3A4
SCHEMBL25323332 0.97 ALDH1A1 (0.47) HSD17B10ALDH1A1ALOX15TSHRCYP3A4
SCHEMBL4232445 0.95 ALDH1A1 (0.42) HSD17B10ALDH1A1ALOX15TSHRCYP3A4
SCHEMBL12700559 0.95 ALDH1A1 (0.44) HSD17B10ALDH1A1ALOX15TSHRCYP3A4
SCHEMBL1507961 0.94 ALDH1A1 (0.45) HSD17B10ALDH1A1ALOX15TSHRCYP3A4
SCHEMBL2570988 0.94 KDM1A (0.42) HSD17B10ALDH1A1ALOX15TSHRCYP3A4
SCHEMBL23709146 0.94 ALDH1A1 (0.45) HSD17B10ALDH1A1ALOX15TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288763-B2 Organic electroluminescence device FUJIFILM CORPORATION (JP) 2012-10-16 US disclosed
US-8183586-B2 Organic electroluminescence device and luminescence apparatus FUJIFILM CORPORATION (JP) 2012-05-22 US disclosed
US-20100193820-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND LUMINESCENCE APPARATUS FUJIFILM CORPORATION (JP) 2010-08-05 US disclosed
US-20100140645-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
US-20080241518-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT UDC IRELAND LIMITED (IE) 2008-10-02 US disclosed