Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817104 | 1.00 | CHRNB2 (0.35) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6919001 | 1.00 | CHRNB2 (0.35) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6816559 | 0.93 | CHRNB2 (0.40) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6817699 | 0.93 | CHRNB2 (0.40) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6816567 | 0.93 | CHRNB2 (0.40) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6920211 | 0.88 | CHRNB2 (0.36) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6917989 | 0.88 | CHRNB2 (0.36) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6917992 | 0.88 | CHRNB2 (0.36) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6915428 | 0.85 | CHRNA7 (0.35) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6917873 | 0.85 | CHRNA7 (0.35) | CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009599-A1 | FIVE-MEMBERED HETEROAROMATIC OLEFINIC AZACYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS INHIBITORS OF NCOTINIC CHOLINERGIC RECEPTORS | TARGACEPT, INC. (US) | 2004-01-29 | — | — | WO | disclosed |