⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18902393 | 0.85 | — | — | |
| SCHEMBL18902442 | 0.85 | — | — | |
| SCHEMBL17340021 | 0.83 | — | — | |
| SCHEMBL13893053 | 0.80 | — | — | |
| SCHEMBL12086504 | 0.79 | — | — | |
| SCHEMBL17366341 | 0.78 | — | — | |
| SCHEMBL13316687 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL20363161 | 0.75 | — | — | |
| SCHEMBL6176593 | 0.72 | — | — | |
| SCHEMBL12154534 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707372-B1 | SPIRO-OXINDOLE MDM2 ANTAGONISTS | UNIV MICHIGAN REGENTS (US) | 2016-12-21 | — | — | EP | disclosed |
| US-20120276196-A1 | Pharmaceutical Compositions of a Neuroactive Steroid and Methods of Use Thereof | EURO-CELTIQUE S.A. (LU) | 2012-11-01 | — | — | US | disclosed |
| US-8183499-B2 | Laser piercing method and processing apparatus | NISSAN TANAKA CORPORATION (JP) | 2012-05-22 | — | — | US | disclosed |
| US-7848912-B2 | System and method for predicting performance of electrical power cables | NOVINIUM, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-20100070250-A1 | SYSTEM AND METHOD FOR PREDICTING PERFORMANCE OF ELECTRICAL POWER CABLES | NOVINIUM, INC. (US) | 2010-03-18 | — | — | US | disclosed |
| US-7643977-B2 | System and method for predicting performance of electrical power cables | NOVINIUM, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070046668-A1 | SYSTEM AND METHOD FOR PREDICTING PERFORMANCE OF ELECTRICAL POWER CABLES | NOVINIUM, INC. (US) | 2007-03-01 | — | — | US | disclosed |