SCHEMBL6817433

SCHEMBL6817433

CN1CCC(Oc2cc(NS(=O)(=O)c3ccc(F)cc3)ccc2C(F)(F)F)C1

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 16/20 0.68
FFAR4 Q5NUL3 1/20 0.49
TP53 P04637 2/20 0.44
PKM P14618 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GHSR Q92847 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6824508 0.94 UTS2R (0.64) UTS2RFFAR4TP53GHSR
SCHEMBL6824514 0.94 UTS2R (0.64) UTS2RFFAR4TP53GHSR
SCHEMBL8342761 0.92 UTS2R (0.68) UTS2RFFAR4
SCHEMBL6820879 0.92 UTS2R (0.70) UTS2RFFAR4
SCHEMBL8342132 0.92 UTS2R (0.68) UTS2RFFAR4
SCHEMBL8339810 0.92 UTS2R (0.70) UTS2RFFAR4
SCHEMBL6824191 0.91 UTS2R (0.67) UTS2RTP53
SCHEMBL8342765 0.91 UTS2R (0.67) UTS2RTP53
SCHEMBL6819749 0.91 UTS2R (0.67) UTS2RTP53
SCHEMBL8342924 0.90 UTS2R (0.68) UTS2RFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043917-A1 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed