Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 17/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | HTR1F | P30939 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339810 | 1.00 | UTS2R (0.70) | UTS2RFFAR1FFAR4HTR6CYP1A2 | |
| SCHEMBL6817433 | 0.92 | UTS2R (0.68) | UTS2RFFAR4 | |
| SCHEMBL8342761 | 0.92 | UTS2R (0.68) | UTS2RFFAR1FFAR4 | |
| SCHEMBL8342132 | 0.92 | UTS2R (0.68) | UTS2RFFAR1FFAR4HTR6 | |
| SCHEMBL8342765 | 0.91 | UTS2R (0.67) | UTS2RHTR6 | |
| SCHEMBL5834910 | 0.90 | UTS2R (0.71) | UTS2RFFAR1FFAR4 | |
| SCHEMBL5834906 | 0.90 | UTS2R (0.71) | UTS2RFFAR1FFAR4 | |
| SCHEMBL8342924 | 0.90 | UTS2R (0.68) | UTS2RFFAR1FFAR4 | |
| SCHEMBL5835553 | 0.89 | UTS2R (0.65) | UTS2RHTR6DRD2DRD3 | |
| SCHEMBL5835561 | 0.89 | UTS2R (0.65) | UTS2RHTR6DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |