Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399077 | 0.82 | DDB1 (0.57) | DDB1CRBNCTSSCTSLCTSB | |
| SCHEMBL6813890 | 0.82 | DDB1 (0.57) | DDB1CRBNCTSSCTSLCTSB | |
| SCHEMBL6821686 | 0.82 | DDB1 (0.52) | DDB1CRBNP2RX7CTSSCTSL | |
| SCHEMBL1399003 | 0.81 | DDB1 (0.55) | DDB1CRBNCTSSCTSLCTSB | |
| SCHEMBL6818881 | 0.78 | DDB1 (0.52) | DDB1CRBNCTSSCTSLCTSB | |
| SCHEMBL1398960 | 0.75 | CRBN (0.60) | DDB1CRBNCASP1CTSSCTSL | |
| SCHEMBL12355229 | 0.73 | DDB1 (0.47) | DDB1CRBNCTSSCTSLCTSB | |
| SCHEMBL8073977 | 0.70 | CTSS (0.46) | DDB1CRBNCTSSCTSLCTSB | |
| SCHEMBL12041931 | 0.70 | DDB1 (0.58) | DDB1CRBNLMNAALDH1A1HTT | |
| SCHEMBL26833122 | 0.69 | DDB1 (0.44) | DDB1CRBNCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022536-A1 | NEW HETEROCYCLIC AMIDE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (US) | 2004-03-18 | — | — | WO | disclosed |