Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 1.00 |
| ▸ | ADRB3 | P13945 | 4/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17086818 | 1.00 | ADRB1 (1.00) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL12648565 | 1.00 | ADRB1 (1.00) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| Hydrochloric Acid SCHEMBL2342247 | 0.99 | ADRB1 (0.97) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| Hydrochloric Acid SCHEMBL2342254 | 0.99 | ADRB1 (0.97) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL9320098 | 0.90 | ADRB1 (0.81) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL10773150 | 0.90 | ADRB1 (0.81) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL9320119 | 0.90 | ADRB1 (0.81) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL10364866 | 0.90 | ADRB1 (0.81) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL9363727 | 0.89 | ADRB1 (0.79) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| Hydrochloric Acid SCHEMBL10364094 | 0.89 | ADRB1 (0.80) | ADRB1ADRB3ADRB2CYP1A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210849-B1 | 2-HYDROXY-3-PHENOXYPROPYL AMINES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-29 | — | — | EP | claimed |
| US-4772631-A | Phenyl ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-20 | — | — | US | claimed |
| EP-0210849-A1 | 2-Hydroxy-3-phenoxypropyl amines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-04 | — | — | EP | claimed |
| WO-2004084881-A1 | METHODS FOR TREATING FUNCTIONAL BOWEL DISORDERS USING α2δ SUBUNIT CALCIUM CHANNEL MODULATORS WITH SMOOTH MUSCLE MODULATORS | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-10-07 | — | — | WO | disclosed |
| US-4977148-A | THERMOGENIC STIMULANTS FOR OBESITY OR DIABETES | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1990-12-11 | — | — | US | disclosed |
| EP-0210849-B1 | 2-HYDROXY-3-PHENOXYPROPYL AMINES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-29 | — | — | EP | disclosed |
| US-4927836-A | OBESITY | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-22 | — | — | US | disclosed |
| EP-0254532-B1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-09 | — | — | EP | disclosed |
| US-4772631-A | Phenyl ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-20 | — | — | US | disclosed |
| EP-0254532-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-27 | — | — | EP | disclosed |
| EP-0210849-A1 | 2-Hydroxy-3-phenoxypropyl amines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-04 | — | — | EP | disclosed |