SCHEMBL6818090

SCHEMBL6818090

N#Cc1ccc(NC(=O)c2ccc(SCc3ccccc3)nc2)c(C(=O)O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 2/20 0.65
CXCR2 P25025 8/20 0.55
MCL1 Q07820 1/20 0.47
BCL2A1 Q16548 1/20 0.47
CXCR1 P25024 2/20 0.44
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NPC1 O15118 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LTC4S Q16873 1/20 0.43
HDAC1 Q13547 1/20 0.43
F10 P00742 2/20 0.42
KDM4E B2RXH2 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6833139 0.99 ALB (0.64) ALBCXCR2MCL1BCL2A1CXCR1
SCHEMBL6818018 0.86 ALB (0.49) ALBCXCR2MCL1BCL2A1KMT2A
Hydrochloric Acid SCHEMBL6821748 0.86 ALB (0.70) ALBCXCR2KMT2AMEN1L3MBTL1
Hydrochloric Acid SCHEMBL6833971 0.84 ALB (0.73) ALBCXCR2MCL1BCL2A1CXCR1
SCHEMBL6833065 0.84 ALB (0.61) ALBCXCR2MCL1BCL2A1CXCR1
SCHEMBL6830644 0.83 ALB (0.77) ALBCXCR2CXCR1KMT2AMEN1
SCHEMBL6918954 0.83 ALB (0.72) ALBCXCR2CXCR1MAPTKMT2A
SCHEMBL6834265 0.83 ALB (0.67) ALBCXCR2MCL1BCL2A1KMT2A
SCHEMBL6833784 0.83 ALB (0.75) ALBCXCR2MCL1BCL2A1CXCR1
SCHEMBL6833946 0.83 ALB (0.76) ALBCXCR2CXCR1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004018428-A1 ANTIBACTERIAL BENZOIC ACID DERIVATIVES PHARMACIA & UPJOHN COMPANY LLC (US) 2004-03-04 WO disclosed