SCHEMBL6833065

SCHEMBL6833065

N#Cc1ccc(NC(=O)c2ccc(SCc3ncon3)nc2)c(C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALB P02768 2/20 0.61
CXCR2 P25025 12/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 1/20 0.39
HTT P42858 1/20 0.39
F10 P00742 2/20 0.38
MCL1 Q07820 1/20 0.36
BCL2A1 Q16548 1/20 0.36
CXCR1 P25024 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6818090 0.84 ALB (0.65) ALBCXCR2KMT2AMEN1L3MBTL1
SCHEMBL6830670 0.83 ALB (0.58) ALBCXCR2KMT2AMEN1L3MBTL1
Hydrochloric Acid SCHEMBL6833139 0.83 ALB (0.64) ALBCXCR2KMT2AMEN1L3MBTL1
Hydrochloric Acid SCHEMBL6821748 0.82 ALB (0.70) ALBCXCR2KMT2AMEN1L3MBTL1
SCHEMBL6833831 0.82 ALB (0.60) ALBCXCR2KMT2AMEN1L3MBTL1
Hydrochloric Acid SCHEMBL6833971 0.81 ALB (0.73) ALBCXCR2KMT2AMEN1L3MBTL1
SCHEMBL6918954 0.80 ALB (0.72) ALBCXCR2KMT2AMEN1L3MBTL1
SCHEMBL6830644 0.80 ALB (0.77) ALBCXCR2KMT2AMEN1L3MBTL1
SCHEMBL6834265 0.80 ALB (0.67) ALBCXCR2KMT2AMEN1L3MBTL1
SCHEMBL6833784 0.80 ALB (0.75) ALBCXCR2KMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 ALB 1417/4885CXCR2 3973/4885KMT2A 2853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.