Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813690 | 0.87 | PPARA (0.53) | PPARAPPARGADAMTS4ITGB3ITGA2B | |
| SCHEMBL6817531 | 0.87 | PPARA (0.53) | PPARAPPARGADAMTS4ITGB3ITGA2B | |
| SCHEMBL6813874 | 0.87 | PPARA (0.53) | PPARAPPARGADAMTS4ITGB3ITGA2B | |
| SCHEMBL6817490 | 0.85 | PPARA (0.51) | PPARAPPARGADAMTS4ITGB3ITGA2B | |
| SCHEMBL6818140 | 0.85 | PPARA (0.51) | PPARAPPARGADAMTS4ITGB3ITGA2B | |
| SCHEMBL6818144 | 0.85 | PPARA (0.51) | PPARAPPARGADAMTS4ITGB3ITGA2B | |
| SCHEMBL6921681 | 0.82 | PPARA (0.54) | PPARAPPARGADAMTS4ITGB3ITGA2B | |
| SCHEMBL5393093 | 0.81 | PPARG (0.72) | PPARAPPARGITGB3ITGA2B | |
| SCHEMBL601719 | 0.81 | PPARG (0.72) | PPARAPPARGITGB3ITGA2B | |
| SCHEMBL5991816 | 0.80 | PPARA (0.60) | PPARAPPARGADAMTS4ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237857-B1 | NEW PHENALKYLOXY-PHENYL DERIVATIVES | ASTRAZENECA AB (SE) | 2004-06-30 | — | — | EP | claimed |
| EP-1237857-B1 | NEW PHENALKYLOXY-PHENYL DERIVATIVES | ASTRAZENECA AB (SE) | 2004-06-30 | — | — | EP | disclosed |