SCHEMBL681815

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2140001	1.00	PDE4D (0.47)	PDE4DPDE4BPDE4APDE4CPRKCQ
	SCHEMBL682909	0.90	PDE4B (0.44)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL875330	0.90	PDE4B (0.44)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL683217	0.88	PDE4B (0.41)	PDE4B
	SCHEMBL874599	0.87	PRKCA (0.47)	PDE4DPDE4BPDE4APDE4CPRKCQ
	SCHEMBL682910	0.87	PRKCA (0.47)	PDE4DPDE4BPDE4APDE4CPRKCQ
	SCHEMBL2139736	0.85	PDE4D (0.48)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL682874	0.85	PDE4D (0.48)	PDE4DPDE4BPDE4APDE4C
	Hydrochloric Acid SCHEMBL875394	0.84	PDE4D (0.47)	PDE4DPDE4BPDE4APDE4C
	Hydrochloric Acid SCHEMBL2139482	0.84	PDE4D (0.47)	PDE4DPDE4BPDE4APDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.