Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.77 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 3/20 | 0.36 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ximelagatran SCHEMBL15908919 | 0.87 | F2 (1.00) | F2PLATPRSS1F10ALDH1A1 | |
| Ximelagatran SCHEMBL4845 | 0.87 | F2 (1.00) | F2PLATPRSS1F10ALDH1A1 | |
| Ximelagatran SCHEMBL19065093 | 0.87 | F2 (1.00) | F2PLATPRSS1F10ALDH1A1 | |
| Ximelagatran SCHEMBL14509860 | 0.87 | F2 (1.00) | F2PLATPRSS1F10ALDH1A1 | |
| SCHEMBL7217026 | 0.86 | F2 (0.76) | F2PLATPRSS1F10ALDH1A1 | |
| Ximelagatran SCHEMBL8039753 | 0.85 | F2 (0.76) | F2PLATPRSS1F10ALDH1A1 | |
| Ximelagatran SCHEMBL14542684 | 0.85 | F2 (0.76) | F2PLATPRSS1F10ALDH1A1 | |
| SCHEMBL8083322 | 0.84 | F2 (0.78) | F2PLATPRSS1F10ALDH1A1 | |
| Ximelagatran SCHEMBL7222774 | 0.81 | F2 (0.88) | F2PLATPRSS1F10ALDH1A1 | |
| SCHEMBL7222186 | 0.81 | F2 (0.72) | F2PLATPRSS1F10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109526-B1 | IMPROVED STABILITY FOR INJECTION SOLUTIONS | ASTRAZENECA AB (SE) | 2004-03-31 | — | — | EP | claimed |