Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813719 | 0.83 | CA12 (0.47) | FFAR1SLC2A1PPARGCA12CA1 | |
| SCHEMBL7243191 | 0.82 | PPARG (0.52) | FFAR1PPARGALOX5PPARA | |
| SCHEMBL6821028 | 0.78 | PPARG (0.47) | FFAR1PPARGALOX5PPARA | |
| SCHEMBL5991810 | 0.77 | PPARG (0.55) | FFAR1PPARGALOX5PPARA | |
| SCHEMBL5991298 | 0.75 | PPARA (0.67) | PPARGPPARA | |
| SCHEMBL5991287 | 0.75 | PPARA (0.67) | PPARGPPARA | |
| SCHEMBL4029473 | 0.75 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL5992000 | 0.74 | PPARG (0.50) | FFAR1RAB9ALTA4HPPARGALOX5 | |
| SCHEMBL5992824 | 0.73 | PPARA (0.56) | FFAR1PPARGPPARA | |
| SCHEMBL5992817 | 0.73 | PPARA (0.56) | FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237857-B1 | NEW PHENALKYLOXY-PHENYL DERIVATIVES | ASTRAZENECA AB (SE) | 2004-06-30 | — | — | EP | disclosed |