Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.47 |
| ▸ | PPARA | Q07869 | 10/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5991960 | 0.89 | PPARA (0.45) | PPARGPPARAALOX5FFAR1PTGES | |
| SCHEMBL6821601 | 0.88 | PPARG (0.48) | PPARGPPARAALOX5FFAR1PTGES | |
| SCHEMBL7243191 | 0.88 | PPARG (0.52) | PPARGPPARAALOX5FFAR1PTGES | |
| SCHEMBL5992824 | 0.85 | PPARA (0.56) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL5992817 | 0.85 | PPARA (0.56) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL5991287 | 0.80 | PPARA (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5991298 | 0.80 | PPARA (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5991810 | 0.80 | PPARG (0.55) | PPARGPPARAALOX5FFAR1PTGES | |
| SCHEMBL5992000 | 0.79 | PPARG (0.50) | PPARGPPARAALOX5FFAR1PTGES | |
| SCHEMBL5992755 | 0.79 | MMP8 (0.45) | PPARGLMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237857-B1 | NEW PHENALKYLOXY-PHENYL DERIVATIVES | ASTRAZENECA AB (SE) | 2004-06-30 | — | — | EP | disclosed |