Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010422 | 0.92 | KMT2A (0.66) | KMT2AALDH1A1CREBBPMEN1NPSR1 | |
| SCHEMBL7465120 | 0.88 | KMT2A (0.78) | KMT2AALDH1A1CREBBPMEN1SMN1; SMN2 | |
| Perchlorate SCHEMBL5784148 | 0.85 | KMT2A (0.59) | KMT2AALDH1A1CREBBPMEN1NPSR1 | |
| SCHEMBL2439155 | 0.82 | KMT2A (0.57) | KMT2AALDH1A1CREBBPMEN1NPSR1 | |
| SCHEMBL3480463 | 0.80 | HSD17B2 (0.59) | KMT2AALDH1A1MEN1NPSR1SMN1; SMN2 | |
| SCHEMBL7361563 | 0.80 | KMT2A (0.65) | KMT2AALDH1A1CREBBPMEN1SMN1; SMN2 | |
| SCHEMBL2848020 | 0.80 | KMT2A (0.61) | KMT2AALDH1A1MEN1SMN1; SMN2TSHR | |
| SCHEMBL2007531 | 0.80 | ALDH1A1 (0.54) | KMT2AALDH1A1CREBBPMEN1NPSR1 | |
| SCHEMBL5531456 | 0.80 | KMT2A (0.54) | KMT2AALDH1A1CREBBPMEN1NPSR1 | |
| SCHEMBL6155851 | 0.77 | KMT2A (0.46) | KMT2AALDH1A1CREBBPMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |