Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.35 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.33 |
| ▸ | STK4 | Q13043 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818763 | 0.90 | EGLN2 (0.37) | TP53POLBMAPTALBHIF1A | |
| SCHEMBL6814223 | 0.89 | HIF1A (0.40) | POLBMAPTALBHIF1A | |
| SCHEMBL6813726 | 0.89 | AGPAT2 (0.37) | RXFP1TP53POLBMAPTALB | |
| SCHEMBL6818738 | 0.88 | RXFP1 (0.40) | RXFP1TP53POLBMAPTALB | |
| SCHEMBL6818713 | 0.88 | EGLN2 (0.37) | TP53POLBMAPTALBHIF1A | |
| SCHEMBL6818851 | 0.88 | HIF1A (0.40) | RXFP1TP53POLBMAPTALB | |
| SCHEMBL6817465 | 0.88 | GSK3A (0.37) | MAPTALBHIF1AEIF4EBP1KDM4E | |
| SCHEMBL6817645 | 0.87 | AGPAT2 (0.37) | RXFP1TP53POLBMAPTALB | |
| SCHEMBL6819350 | 0.87 | HIF1A (0.39) | POLBMAPTALBHIF1A | |
| SCHEMBL6814736 | 0.87 | TP53 (0.37) | RXFP1TP53POLBMAPTALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |