⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814845 | 1.00 | — | — | |
| SCHEMBL11320669 | 0.49 | LPO (0.44) | — | |
| SCHEMBL14264338 | 0.46 | — | — | |
| SCHEMBL3050104 | 0.43 | LPO (0.37) | — | |
| Hexamethylbenzene SCHEMBL10609849 | 0.36 | RXFP1 (0.31) | — | |
| SCHEMBL682487 | 0.36 | — | — | |
| Hexamethylbenzene SCHEMBL3999978 | 0.34 | — | — | |
| Hexamethylbenzene SCHEMBL3999655 | 0.34 | — | — | |
| Hexamethylbenzene SCHEMBL8521014 | 0.34 | — | — | |
| Hydrochloric Acid SCHEMBL1490253 | 0.34 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809195-B1 | COMPRISES A MODIFIED PHOSPHORAMIDITE PROTOCOL IN WHICH OXIDATION AND CAPPING STEPS ARE COMBINED INTO A SINGLE STEP; INCREASED EFFICIENCY; SOLID PHASE SYNTHESIS | ISIS PHARMACEUTICALS, INC. | 2004-10-26 | — | — | US | disclosed |
| US-20040198972-A1 | Processes for the preparation of oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2004-10-07 | — | — | US | disclosed |
| US-6762281-B2 | GENERATING PREFERENTIAL OLIGOMERS; GENERATE OLIGOMER, DEPROTECT, EXPOSE TO PHOSPHOROUS, OXIDIZE, EXPOSE TO SULFUR, CLEAVE, RECOVER PRODUCT | ISIS PHARMACEUTICALS, INC. | 2004-07-13 | — | — | US | disclosed |
| US-6559279-B1 | Generation of peptide linked oligomers; generate solid support, expose to deprotecting agent, incubate with nucleoside, cap, cleave and recover peptide derivative | ISIS PHARMACEUTICALS, INC. | 2003-05-06 | — | — | US | disclosed |
| US-20020156235-A1 | Process for preparing peptide derivatized oligomeric compounds | IONIS PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | disclosed |
| WO-2002020544-A1 | PROCESS FOR PREPARING PEPTIDE DERIVATIZED OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2002-03-14 | — | — | WO | disclosed |
| EP-0061446-B1 | CHEMICALLY SENSITIZED SILVER HALIDE PHOTOGRAPHIC EMULSIONS AND COLOR PHOTOGRAPHIC ELEMENTS CONTAINING SAID EMULSIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-05-15 | — | — | EP | disclosed |
| EP-0061446-A4 | CHEMICALLY SENSITIZED SILVER HALIDE PHOTOGRAPHIC EMULSIONS AND COLOR PHOTOGRAPHIC ELEMENTS CONTAINING SAID EMULSIONS. | MINNESOTA MINING & MFG (US) | 1983-04-18 | — | — | EP | disclosed |
| EP-0061446-A1 | CHEMICALLY SENSITIZED SILVER HALIDE PHOTOGRAPHIC EMULSIONS AND COLOR PHOTOGRAPHIC ELEMENTS CONTAINING SAID EMULSIONS. | MINNESOTA MINING & MFG (US) | 1982-10-06 | — | — | EP | disclosed |
| WO-1982001260-A1 | CHEMICALLY SENSITIZED SILVER HALIDE PHOTOGRAPHIC EMULSIONS AND COLOR PHOTOGRAPHIC ELEMENTS CONTAINING SAID EMULSIONS | MINNESOTA MINING & MFG (US) | 1982-04-15 | — | — | WO | disclosed |