Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125784 | 0.78 | KDM4E (0.49) | CYP1A2CYP2A6GAAL3MBTL1ELANE | |
| SCHEMBL6821557 | 0.76 | KDM4E (0.43) | CYP1A2CYP2A6DHODHCYP3A4CYP2C8 | |
| SCHEMBL2123532 | 0.74 | NR4A2 (0.50) | CYP1A2CYP2A6DHODHSMN1; SMN2KDM4E | |
| SCHEMBL16438151 | 0.73 | CCR1 (0.46) | CYP1A2CYP2A6DHODHCYP3A4CYP2C8 | |
| SCHEMBL3796528 | 0.73 | CCR1 (0.41) | CYP1A2CYP3A4GAAHTTSMN1; SMN2 | |
| SCHEMBL8139070 | 0.72 | DHODH (0.39) | CYP1A2CYP2A6DHODHCYP3A4CYP2C8 | |
| SCHEMBL8361710 | 0.72 | KDM4E (0.46) | CYP1A2CYP2D6CYP2C9CYP2C19KDM4E | |
| SCHEMBL2124840 | 0.71 | PIK3CA (0.37) | CYP1A2CYP3A4CYP2D6CYP2C9GAA | |
| SCHEMBL2124149 | 0.69 | ALDH1A1 (0.50) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7774725 | 0.69 | KDM4E (0.68) | GAAHTTSMN1; SMN2PARP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067513-A1 | ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS | OY JUVANTIA PHARMA LTD (FI) | 2004-08-12 | — | — | WO | disclosed |