Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818628 | 1.00 | TUBB1 (0.64) | TUBB1KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL584263 | 0.86 | KDM4E (0.73) | TUBB1KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL584262 | 0.86 | KDM4E (0.73) | TUBB1KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL30548412 | 0.86 | TUBB1 (0.66) | TUBB1KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL29090925 | 0.86 | TUBB1 (0.66) | TUBB1KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL24164775 | 0.86 | TUBB1 (0.66) | TUBB1KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL1589619 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL29503043 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL1589618 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| Hydrochloric Acid SCHEMBL6818633 | 0.84 | KDM4E (0.71) | TUBB1KDM4EALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |