Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.61 |
| ▸ | JUN | P05412 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29503043 | 1.00 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2HPGDALOX15 | |
| SCHEMBL1589619 | 1.00 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2HPGDALOX15 | |
| SCHEMBL4128281 | 0.89 | JUN (0.78) | KDM4EALDH1A1SMN1; SMN2HPGDALOX15 | |
| SCHEMBL4121496 | 0.89 | JUN (0.78) | KDM4EALDH1A1SMN1; SMN2HPGDALOX15 | |
| SCHEMBL17340449 | 0.89 | MAOB (0.63) | KDM4EALDH1A1SMN1; SMN2HPGDALOX15 | |
| SCHEMBL25262773 | 0.88 | APP (0.64) | KDM4EALDH1A1SMN1; SMN2HPGDALOX15 | |
| SCHEMBL29096342 | 0.88 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2HPGDALOX15 | |
| SCHEMBL30448694 | 0.88 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2HPGDALOX15 | |
| SCHEMBL1204987 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDALOX15 | |
| SCHEMBL3040060 | 0.87 | CYP2D6 (0.77) | KDM4EALDH1A1HPGDALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118029135-A | Antibacterial acrylic knitted fabric and preparation method thereof | 上海朔言化工有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-114349653-B | Synthetic method of tranilast | 西安岳达生物科技股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-114349653-A | Synthetic method of tranilast | 北京岳达生物科技有限公司 | 2022-04-15 | — | — | CN | claimed |
| JP-6041155-A | — | — | None | — | — | JP | disclosed |
| CN-118490691-A | Use of adenosine A2A receptor antagonists in the treatment and prevention of glaucoma | 温州医科大学附属眼视光医院 | 2024-08-16 | — | — | CN | disclosed |
| CN-118029135-A | Antibacterial acrylic knitted fabric and preparation method thereof | 上海朔言化工有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-118029135-A | Antibacterial acrylic knitted fabric and preparation method thereof | 上海朔言化工有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114349653-B | Synthetic method of tranilast | 西安岳达生物科技股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-114349653-B | Synthetic method of tranilast | 西安岳达生物科技股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-114349653-A | Synthetic method of tranilast | 北京岳达生物科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114349653-A | Synthetic method of tranilast | 北京岳达生物科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-0152799-A1 | Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them | PULITZER ITALIANA S.p.A. (IT) | 1985-08-28 | — | — | EP | disclosed |
| EP-0140327-A2 | Bis-dioxopiperazine derivatives, process for their preparation, antitumor agents comprising them and compositions containing them | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-08 | — | — | EP | disclosed |
| US-4402981-A | ANTIULCER AGENT | KALI-CHEMIE PHARMA, GMBH (DE) | 1983-09-06 | — | — | US | disclosed |
| US-4337270-A | ANTIALLERGENS; ANTIANAPHYLACTIC AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1982-06-29 | — | — | US | disclosed |
| US-4191770-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1980-03-04 | — | — | US | disclosed |
| US-4070484-A | Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same | KISSEI PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |
| US-4026896-A | ANTIALLERGENS | KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (KISSEI PHARMACEUTICAL CO. LTD.) (JA) | 1977-05-31 | — | — | US | disclosed |
| US-3940422-A | ANTIALLERGEN | KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (JA) | 1976-02-24 | — | — | US | disclosed |
| US-3933826-A | ANALGESICS, VASODILATORS, HYPOTENSIVES | NIPPON CHEMIPHAR CO., LTD. (JA) | 1976-01-20 | — | — | US | disclosed |