Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818676 | 0.92 | POLB (0.45) | AKR1C2AKR1C1NPSR1L3MBTL1POLB | |
| SCHEMBL6835830 | 0.83 | AKR1C2 (0.46) | AKR1C2AKR1C1NPSR1L3MBTL1POLB | |
| SCHEMBL6833147 | 0.83 | POLB (0.53) | AKR1C2AKR1C1POLBMEN1KMT2A | |
| SCHEMBL6833223 | 0.80 | POLB (0.52) | AKR1C2AKR1C1POLBMEN1KMT2A | |
| SCHEMBL6819558 | 0.80 | POLB (0.51) | AKR1C2AKR1C1POLBMEN1KMT2A | |
| SCHEMBL6818627 | 0.73 | ALB (0.59) | AKR1C2AKR1C1POLBMEN1KMT2A | |
| SCHEMBL6834113 | 0.73 | KDM4E (0.46) | AKR1C2AKR1C1POLBMEN1KMT2A | |
| SCHEMBL6817525 | 0.73 | NPSR1 (0.49) | AKR1C2AKR1C1NPSR1L3MBTL1KDM4E | |
| SCHEMBL6818760 | 0.70 | PLK1 (0.49) | AKR1C2AKR1C1KDM4EALBHSD17B10 | |
| SCHEMBL6835841 | 0.70 | ALB (0.49) | NPSR1L3MBTL1MEN1KMT2AALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |