Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.51 |
| ▸ | PLK1 | P53350 | 5/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833223 | 0.97 | POLB (0.52) | POLBAKR1C2AKR1C1PLK1STING1 | |
| SCHEMBL6819558 | 0.96 | POLB (0.51) | POLBAKR1C2AKR1C1PLK1STING1 | |
| SCHEMBL6818676 | 0.92 | POLB (0.45) | POLBAKR1C2AKR1C1PLK1STING1 | |
| SCHEMBL6834113 | 0.89 | KDM4E (0.46) | POLBAKR1C2AKR1C1PLK1KDM4E | |
| SCHEMBL6818627 | 0.87 | ALB (0.59) | POLBAKR1C2AKR1C1PLK1STING1 | |
| SCHEMBL6818760 | 0.86 | PLK1 (0.49) | AKR1C2AKR1C1PLK1KDM4EALB | |
| SCHEMBL6834094 | 0.85 | ALB (0.59) | AKR1C2AKR1C1PLK1STING1KDM4E | |
| SCHEMBL6830132 | 0.85 | PLK1 (0.51) | AKR1C2AKR1C1PLK1KDM4EALB | |
| SCHEMBL6818682 | 0.83 | AKR1C2 (0.38) | POLBAKR1C2AKR1C1PLK1STING1 | |
| SCHEMBL6833242 | 0.83 | PLK1 (0.58) | POLBAKR1C2AKR1C1PLK1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | POLB 637/4885AKR1C2 2596/4885AKR1C1 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.