Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.33 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818959 | 0.98 | HSP90AB1 (0.35) | HSP90AB1MAPK14EGLN2EGLN1PPARG | |
| SCHEMBL6822517 | 0.91 | EGLN2 (0.39) | MAPK14EGLN2PPARGALBPOLB | |
| SCHEMBL6818615 | 0.90 | RORC (0.35) | HSP90AB1PPARGALBBACE1RORC | |
| SCHEMBL6822410 | 0.89 | EGLN2 (0.38) | MAPK14EGLN2PPARGALBPOLB | |
| SCHEMBL6818290 | 0.89 | EGLN2 (0.37) | MAPK14EGLN2PPARGALBRORC | |
| SCHEMBL6814235 | 0.88 | EGLN2 (0.37) | MAPK14EGLN2PPARGALBRORC | |
| SCHEMBL6819036 | 0.88 | RORC (0.35) | HSP90AB1PPARGALBRORCPDE10A | |
| SCHEMBL6818149 | 0.88 | LRRK2 (0.36) | EGLN2ALBPOLBTP53MAPT | |
| SCHEMBL6822324 | 0.87 | RXFP1 (0.40) | EGLN2PPARGALBRORCPOLB | |
| SCHEMBL6818824 | 0.85 | HIF1A (0.37) | MAPK14EGLN2ALBPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |