Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6484781 | 0.97 | PTGER4 (0.41) | PTGER4KDM4ECACNA1GCACNA1HCACNA1I | |
| SCHEMBL6490897 | 0.89 | KDM5A (0.38) | MMP13P2RX7PDE2A | |
| SCHEMBL6476549 | 0.87 | NR1H4 (0.44) | PTGER4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6819160 | 0.84 | KDM4E (0.35) | PTGER4KDM4ECACNA1GCACNA1HCACNA1I | |
| SCHEMBL6289370 | 0.80 | MMP13 (0.46) | PTGER4MMP13MAPTKLK1 | |
| SCHEMBL6478088 | 0.79 | PTGER4 (0.41) | PTGER4KDM4ECACNA1GCACNA1HCACNA1I | |
| SCHEMBL6819023 | 0.79 | MMP13 (0.38) | PTGER4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6819026 | 0.75 | MAPT (0.35) | KDM4EALDH1A1HPGDHSD17B10PDE2A | |
| SCHEMBL6489420 | 0.75 | GRM4 (0.35) | P2RX7RXFP1 | |
| SCHEMBL6289023 | 0.74 | CNR2 (0.41) | PTGER4CACNA1GCACNA1HCACNA1IHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |