Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 8/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.46 |
| ▸ | SRC | P12931 | 7/20 | 0.46 |
| ▸ | ABL1 | P00519 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.46 |
| ▸ | PRKDC | P78527 | 4/20 | 0.46 |
| ▸ | HCK | P08631 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.46 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL682317 | 0.87 | PIK3CG (0.49) | PIK3CGPIK3CDSRCABL1EGFR | |
| SCHEMBL680950 | 0.81 | PIK3CG (0.60) | PIK3CGPIK3CDSRCABL1EGFR | |
| SCHEMBL685194 | 0.80 | PIK3CG (0.72) | PIK3CGPIK3CDSRCABL1EGFR | |
| SCHEMBL681856 | 0.78 | PIK3CD (0.65) | PIK3CGPIK3CDPI4KBPI4KAPI4K2B | |
| SCHEMBL1882467 | 0.77 | PIK3CD (0.46) | PIK3CGPIK3CDSRCABL1EGFR | |
| SCHEMBL681835 | 0.76 | PIK3CG (1.00) | PIK3CGPIK3CDSRCABL1EGFR | |
| SCHEMBL682358 | 0.75 | PIK3CG (0.67) | PIK3CGPIK3CDSRCABL1EGFR | |
| SCHEMBL681708 | 0.73 | PIK3CG (0.81) | PIK3CGPIK3CDSRCABL1EGFR | |
| SCHEMBL681991 | 0.71 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3C2BKDM4EALDH1A1 | |
| SCHEMBL1885635 | 0.70 | PIK3CD (0.38) | PIK3CGPIK3CDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281866-A1 | HETEROCYCLIC KINASE INHIBITORS | INTELLIKINE, INC. (US) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281866-A1 | HETEROCYCLIC KINASE INHIBITORS | MAP3K13, MAP3K3, CDK3 | PIK3CG 191/4885PIK3CD 147/4885SRC 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.