SCHEMBL681932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL877291	1.00	NR1H2 (0.40)	NR1H2NR1H3ABCB1SLC6A2SLC6A4
	SCHEMBL877368	0.89	PDE4B (0.44)	NR1H2NR1H3MC4RMC3RMC1R
	SCHEMBL683334	0.89	PDE4B (0.44)	NR1H2NR1H3MC4RMC3RMC1R
	SCHEMBL877038	0.89	PDE4B (0.42)	NR1H2NR1H3MEN1KMT2AMC4R
	SCHEMBL683012	0.89	PDE4B (0.42)	NR1H2NR1H3MEN1KMT2AMC4R
	SCHEMBL873399	0.86	NR1H2 (0.44)	NR1H2NR1H3ABCB1HCRTR1MEN1
	SCHEMBL873788	0.86	NR1H2 (0.44)	NR1H2NR1H3ABCB1HCRTR1MEN1
	SCHEMBL683023	0.85	NR1H2 (0.43)	NR1H2NR1H3ABCB1HCRTR1DPP4
	SCHEMBL2138237	0.85	NR1H2 (0.43)	NR1H2NR1H3ABCB1HCRTR1DPP4
	SCHEMBL873991	0.85	NR1H2 (0.43)	NR1H2NR1H3ABCB1HCRTR1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.