SCHEMBL683012

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL877038	1.00	PDE4B (0.42)	PDE4BNR1H2NR1H3MC4RMC3R
	SCHEMBL877368	0.98	PDE4B (0.44)	PDE4BNR1H2NR1H3MC4RMC3R
	SCHEMBL683334	0.98	PDE4B (0.44)	PDE4BNR1H2NR1H3MC4RMC3R
	SCHEMBL681932	0.89	NR1H2 (0.40)	NR1H2NR1H3MC4RMC3RMC1R
	SCHEMBL877291	0.89	NR1H2 (0.40)	NR1H2NR1H3MC4RMC3RMC1R
	SCHEMBL682783	0.88	ROCK2 (0.46)	PDE4BNR1H2NR1H3MC4RMC3R
	SCHEMBL877001	0.88	ROCK2 (0.46)	PDE4BNR1H2NR1H3MC4RMC3R
	SCHEMBL877360	0.87	PDE4B (0.41)	PDE4BNR1H2NR1H3PDE4APDE4C
	SCHEMBL683333	0.87	PDE4B (0.41)	PDE4BNR1H2NR1H3PDE4APDE4C
	SCHEMBL2135324	0.87	PDE4B (0.47)	PDE4BNR1H2NR1H3PDE4APDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.