SCHEMBL681940

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2137930	1.00	NR1H2 (0.43)	NR1H2NR1H3KDM4EALDH1A1HPGD
	SCHEMBL683023	0.93	NR1H2 (0.43)	NR1H2NR1H3KDM4EALDH1A1HPGD
	SCHEMBL2138237	0.93	NR1H2 (0.43)	NR1H2NR1H3KDM4EALDH1A1HPGD
	SCHEMBL683366	0.92	KDM4E (0.41)	NR1H2NR1H3KDM4EALDH1A1HPGD
	SCHEMBL2139046	0.92	KDM4E (0.41)	NR1H2NR1H3KDM4EALDH1A1HPGD
	SCHEMBL682749	0.90	PDE4B (0.46)	NR1H2NR1H3HCRTR1HCRTR2
	SCHEMBL2134832	0.90	PDE4B (0.46)	NR1H2NR1H3HCRTR1HCRTR2
	SCHEMBL877437	0.90	PDE4B (0.44)	NR1H2NR1H3KDM4EALDH1A1HPGD
	SCHEMBL682585	0.90	PDE4B (0.44)	NR1H2NR1H3KDM4EALDH1A1HPGD
	SCHEMBL2139357	0.89	PDE4D (0.45)	NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.