SCHEMBL682585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL877437	1.00	PDE4B (0.44)	PDE4BNR1H2NR1H3HCRTR1HCRTR2
	SCHEMBL682749	0.98	PDE4B (0.46)	PDE4BNR1H2NR1H3HCRTR1HCRTR2
	SCHEMBL2134832	0.98	PDE4B (0.46)	PDE4BNR1H2NR1H3HCRTR1HCRTR2
	SCHEMBL681978	0.93	HCRTR1 (0.40)	PDE4BHCRTR1HCRTR2DPP4KDM4E
	SCHEMBL878088	0.93	HCRTR1 (0.40)	PDE4BHCRTR1HCRTR2DPP4KDM4E
	SCHEMBL877075	0.92	CYP3A4 (0.43)	PDE4BNR1H2NR1H3HCRTR1HCRTR2
	SCHEMBL877074	0.92	CYP3A4 (0.43)	PDE4BNR1H2NR1H3HCRTR1HCRTR2
	SCHEMBL2139357	0.91	PDE4D (0.45)	PDE4BNR1H2NR1H3PDE4APDE4C
	SCHEMBL682994	0.91	PDE4D (0.45)	PDE4BNR1H2NR1H3PDE4APDE4C
	SCHEMBL2140445	0.90	PDE4B (0.44)	PDE4BNR1H2NR1H3HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.