Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844676 | 0.89 | NPC1 (0.43) | MAPTARNPC1NOD2NOD1 | |
| SCHEMBL6805379 | 0.82 | AR (0.39) | MAPTARNPC1NOD2NOD1 | |
| SCHEMBL1299290 | 0.80 | MAPT (0.53) | MAPTARNPC1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL2237158 | 0.79 | MAPT (0.52) | MAPTARNPC1MEN1KMT2A | |
| SCHEMBL5680354 | 0.78 | NPC1 (0.45) | MAPTARNPC1NOD2NOD1 | |
| SCHEMBL5889676 | 0.78 | NPC1 (0.47) | MAPTARNPC1NOD2NOD1 | |
| SCHEMBL7258024 | 0.75 | NPC1 (0.44) | MAPTARNPC1NOD2NOD1 | |
| SCHEMBL20644785 | 0.75 | AR (0.46) | MAPTARNPC1NOD2NOD1 | |
| SCHEMBL26106290 | 0.75 | NPC1 (0.44) | MAPTARNPC1NOD2NOD1 | |
| SCHEMBL14099809 | 0.75 | NPC1 (0.44) | MAPTARNPC1NOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467969-A2 | DNA MINOR GROOVE BINDING COMPOUNDS | The University of Strathclyde (GB) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003059881-A2 | DNA MINOR GROOVE BINDING COMPOUNDS | UNIVERSITY OF STRATHCLYDE (GB) | 2003-07-24 | — | — | WO | disclosed |