Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 17/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820238 | 0.85 | SRD5A1 (0.62) | SRD5A1KMT2A | |
| SCHEMBL6819781 | 0.77 | SRD5A1 (1.00) | SRD5A1 | |
| SCHEMBL6819849 | 0.77 | SRD5A1 (1.00) | SRD5A1 | |
| SCHEMBL6822962 | 0.76 | SRD5A1 (0.54) | SRD5A1KMT2A | |
| SCHEMBL6822967 | 0.75 | SRD5A1 (0.64) | SRD5A1 | |
| SCHEMBL6820075 | 0.66 | SRD5A1 (1.00) | SRD5A1KMT2A | |
| SCHEMBL6819774 | 0.66 | SRD5A1 (1.00) | SRD5A1 | |
| SCHEMBL6820284 | 0.65 | SRD5A1 (0.74) | SRD5A1 | |
| SCHEMBL6820079 | 0.62 | SRD5A1 (1.00) | SRD5A1KMT2A | |
| SCHEMBL6820470 | 0.62 | SRD5A1 (0.67) | SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102765-B1 | PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2003-09-17 | — | — | EP | claimed |
| US-6723850-B1 | N-ALKYLATION OF THE THIOAMIDE WITH A VINYL KETONE IN PRESENCE OF A STRONG BASE; 6-CHLORO-(1H)-3,4-DIHYDROQUINOLIN-2-THIONE REACTED WITH ETHYL VINYL KETONE | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-04-20 | — | — | US | disclosed |
| EP-1102765-B1 | PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2003-09-17 | — | — | EP | disclosed |