Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 15/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815740 | 0.80 | AADAT (0.38) | SRD5A1NOTUM | |
| SCHEMBL6820051 | 0.78 | SRD5A1 (0.64) | SRD5A1NOTUMROCK1CYP11B2 | |
| SCHEMBL6820138 | 0.78 | SRD5A1 (0.64) | SRD5A1MAPTNOTUMROCK1 | |
| SCHEMBL6819931 | 0.76 | SRD5A1 (0.63) | SRD5A1KMT2A | |
| SCHEMBL6823141 | 0.70 | SRD5A1 (1.00) | SRD5A1NOTUMROCK1 | |
| SCHEMBL6823140 | 0.63 | NOTUM (0.45) | SRD5A1MAPTNOTUMROCK1 | |
| SCHEMBL6822967 | 0.61 | SRD5A1 (0.64) | SRD5A1 | |
| SCHEMBL6819781 | 0.61 | SRD5A1 (1.00) | SRD5A1NOTUM | |
| SCHEMBL6819849 | 0.61 | SRD5A1 (1.00) | SRD5A1MAPT | |
| SCHEMBL13242322 | 0.60 | HTR2C (0.53) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102765-B1 | PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2003-09-17 | — | — | EP | claimed |
| US-6723850-B1 | N-ALKYLATION OF THE THIOAMIDE WITH A VINYL KETONE IN PRESENCE OF A STRONG BASE; 6-CHLORO-(1H)-3,4-DIHYDROQUINOLIN-2-THIONE REACTED WITH ETHYL VINYL KETONE | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-04-20 | — | — | US | disclosed |
| EP-1102765-B1 | PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2003-09-17 | — | — | EP | disclosed |