Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722541 | 0.81 | — | — | |
| SCHEMBL6540534 | 0.79 | — | — | |
| SCHEMBL79088 | 0.79 | — | — | |
| SCHEMBL2126594 | 0.79 | — | — | |
| SCHEMBL9651831 | 0.79 | NPC1 (0.45) | CYP1A2MEN1NPC1RAB9AKMT2A | |
| Zinc Ion SCHEMBL28664661 | 0.77 | CYP1A2 (0.42) | CYP1A2TSHRHDAC8HDAC6ATM | |
| SCHEMBL5490908 | 0.77 | TSHR (0.46) | CYP1A2TSHRHDAC8HDAC6ATM | |
| SCHEMBL5640920 | 0.74 | — | — | |
| SCHEMBL792605 | 0.74 | — | — | |
| SCHEMBL4263883 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689904-B | Preparation method of triazole sulfur (selenium) ketone derivative | 华南农业大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-111606858-B | Preparation method of imidazole sulfur (selenium) ketone derivative | 华南农业大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-111689904-A | Preparation method of triazole sulfur (selenium) ketone derivative | 华南农业大学 | 2020-09-22 | — | — | CN | disclosed |
| CN-111606858-A | Preparation method of imidazole sulfur (selenium) ketone derivative | 华南农业大学 | 2020-09-01 | — | — | CN | disclosed |
| CN-109020897-B | Azole sulfur (selenium) ketone derivative and preparation method and application thereof | 华南农业大学 | 2020-08-18 | — | — | CN | disclosed |
| US-20040044065-A1 | Radiometal complexes of 2-pyrrolylthiones and their use as radiopharmaceuticals for imaging and therapy | DOLPHIN DAVID H (CA) | 2004-03-04 | — | — | US | disclosed |
| US-6613304-B2 | For imaging renal tissues | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2003-09-02 | — | — | US | disclosed |
| EP-1296721-A2 | RADIOMETAL COMPLEXES OF 2-PYRROLYLTHIONES FOR IMAGING AND THERAPY | The University of British Columbia (CA) | 2003-04-02 | — | — | EP | disclosed |
| US-20020102209-A1 | Radiometal complexes of 2-pyrrolylthiones and their use as radiopharmaceuticals for imaging and therapy | UNIVERSITE DE SHERBROOKE (CA) | 2002-08-01 | — | — | US | disclosed |
| WO-2001080906-A9 | RADIOMETAL COMPLEXES OF 2-PYRROLYLTHIONES FOR IMAGING A THERAPY | UNIV BRITISH COLUMBIA (CA) | 2002-02-21 | — | — | WO | disclosed |
| WO-2001080906-A2 | RADIOMETAL COMPLEXES OF 2-PYRROLYLTHIONES FOR IMAGING A THERAPY | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020102209-A1 | Radiometal complexes of 2-pyrrolylthiones and their use as radiopharmaceuticals for imaging and therapy | MPI, PYCR1, PAICS | CYP1A2 4331/4885TSHR 485/4885HDAC8 3928/4885 |
| US-20040044065-A1 | Radiometal complexes of 2-pyrrolylthiones and their use as radiopharmaceuticals for imaging and therapy | MPI, PYCR1, PAICS | CYP1A2 4331/4885TSHR 485/4885HDAC8 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.