SCHEMBL682012

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2134576	1.00	HCRTR1 (0.44)	HCRTR1HCRTR2PDE4BPDE4APDE4C
	SCHEMBL2141463	0.98	HCRTR1 (0.44)	HCRTR1HCRTR2PDE4BPDE4APDE4C
	SCHEMBL683087	0.98	HCRTR1 (0.44)	HCRTR1HCRTR2PDE4BPDE4APDE4C
	SCHEMBL876960	0.86	PDE4B (0.39)	HCRTR1HCRTR2PDE4BPDE4APDE4C
	SCHEMBL683379	0.86	PDE4B (0.39)	HCRTR1HCRTR2PDE4BPDE4APDE4C
	SCHEMBL2085532	0.85	PDE4B (0.49)	PDE4BPDE4APDE4CPDE4DNR1H2
	SCHEMBL683245	0.85	PDE4B (0.49)	PDE4BPDE4APDE4CPDE4DNR1H2
	SCHEMBL682540	0.85	PDE4B (0.49)	PDE4BPDE4APDE4CPDE4DNR1H2
	SCHEMBL2138899	0.85	PDE4B (0.49)	PDE4BPDE4APDE4CPDE4DNR1H2
	SCHEMBL682749	0.84	PDE4B (0.46)	HCRTR1HCRTR2PDE4BPDE4APDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.