SCHEMBL683379

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL876960	1.00	PDE4B (0.39)	PDE4BPDE4DPDE4APDE4CSLC5A7
	SCHEMBL683087	0.88	HCRTR1 (0.44)	PDE4BPDE4DPDE4APDE4CCCR1
	SCHEMBL2141463	0.88	HCRTR1 (0.44)	PDE4BPDE4DPDE4APDE4CCCR1
	SCHEMBL2134576	0.86	HCRTR1 (0.44)	PDE4BPDE4DPDE4APDE4CHCRTR1
	SCHEMBL682012	0.86	HCRTR1 (0.44)	PDE4BPDE4DPDE4APDE4CHCRTR1
	SCHEMBL876472	0.85	PDE4B (0.39)	PDE4BPDE4DPDE4APDE4CCCR1
	SCHEMBL876471	0.85	PDE4B (0.39)	PDE4BPDE4DPDE4APDE4CCCR1
	SCHEMBL877365	0.82	PDE4B (0.48)	PDE4BPDE4DPDE4APDE4CFFAR4
	SCHEMBL682607	0.82	PDE4B (0.48)	PDE4BPDE4DPDE4APDE4CFFAR4
	SCHEMBL682764	0.82	PDE4B (0.41)	PDE4BPDE4DPDE4APDE4CFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.