Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 5/20 | 0.60 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15022110 | 0.88 | KDM4E (0.50) | EIF2AK4GPBAR1HSD17B10ALKTRPV1 | |
| SCHEMBL12184995 | 0.88 | KDM4E (0.50) | EIF2AK4GPBAR1HSD17B10ALKTRPV1 | |
| SCHEMBL12291584 | 0.84 | TRPV1 (0.50) | GAATRPV1KDM4EALDH1A1HPGD | |
| SCHEMBL28639336 | 0.81 | EIF2AK4 (0.43) | EIF2AK4GPBAR1TRPV1BTK | |
| SCHEMBL12185358 | 0.81 | ALDH1A1 (0.54) | GPBAR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL2635948 | 0.81 | ALDH1A1 (0.54) | GPBAR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL29438234 | 0.81 | ALDH1A1 (0.54) | GPBAR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL28828266 | 0.80 | EIF2AK4 (0.53) | EIF2AK4PBK | |
| SCHEMBL20445954 | 0.80 | SMPD3 (0.48) | GPBAR1TRPV1ALDH1A1BTK | |
| SCHEMBL1290812 | 0.79 | GPBAR1 (0.57) | EIF2AK4PBKGPBAR1GAACDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074287-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |