Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 13/20 | 0.59 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | IL1B | P01584 | 3/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398772 | 0.93 | HCRTR1 (0.51) | HCRTR1HCRTR2KDM1AOPRD1IL1B | |
| SCHEMBL1572370 | 0.80 | HCRTR1 (0.42) | HCRTR1HCRTR2IL1BP2RX7KDM4E | |
| SCHEMBL2930345 | 0.79 | HCRTR1 (0.49) | HCRTR1HCRTR2IL1BP2RX7KDM4E | |
| SCHEMBL2930343 | 0.79 | HCRTR1 (0.49) | HCRTR1HCRTR2IL1BP2RX7KDM4E | |
| SCHEMBL1339577 | 0.79 | HCRTR1 (0.49) | HCRTR1HCRTR2IL1BP2RX7KDM4E | |
| SCHEMBL28153227 | 0.78 | KDM1A (0.50) | HCRTR1HCRTR2KDM1AOPRD1IL1B | |
| SCHEMBL6223223 | 0.78 | KDM4E (0.64) | HCRTR1HCRTR2KDM1AOPRD1FPR3 | |
| SCHEMBL6223221 | 0.78 | KDM4E (0.64) | HCRTR1HCRTR2KDM1AOPRD1FPR3 | |
| SCHEMBL983914 | 0.76 | HCRTR1 (0.43) | HCRTR1HCRTR2IL1BP2RX7KDM4E | |
| SCHEMBL13947480 | 0.75 | MMP13 (0.52) | HCRTR1HCRTR2KDM1AOPRD1IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041807-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-05-21 | — | — | WO | disclosed |