Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199801 | 0.82 | CA2 (0.52) | CA2CA1GRIK1SLC1A2SLC1A1 | |
| SCHEMBL17199809 | 0.81 | CA2 (0.55) | CA2CA1GRIK1SLC1A2SLC1A1 | |
| SCHEMBL10339951 | 0.79 | HDAC1 (0.55) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL358441 | 0.79 | HDAC1 (0.55) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL3078724 | 0.79 | — | — | |
| SCHEMBL6959633 | 0.78 | — | — | |
| SCHEMBL9624847 | 0.78 | HDAC1 (0.48) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL8003111 | 0.78 | CA2 (0.68) | TDP1TSHRCYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL9624567 | 0.77 | HDAC1 (0.52) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL4726173 | 0.77 | HDAC1 (0.52) | HDAC7HDAC8HDAC6HDAC9HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046153-A1 | PRODRUG ESTERS OF CEFTRIAXONE | RANBAXY LABORATORIES LIMITED (IN) | 2004-06-03 | — | — | WO | claimed |
| EP-0295100-B1 | Methoxymethyl compounds | ERBA CARLO SPA (IT) | 1994-09-14 | — | — | EP | claimed |
| US-4952577-A | ANTIBIOTICS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-08-28 | — | — | US | claimed |
| EP-0295100-A1 | Methoxymethyl compounds | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-12-14 | — | — | EP | claimed |
| US-20150119346-A1 | GLYCOSYLATED VALPROIC ACID ANALOGS AND USES THEREOF | Chromatin Technologies | 2015-04-30 | — | — | US | disclosed |
| US-8921533-B2 | Glycosylated valproic acid analogs and uses thereof | Chromatin Technologies (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130029924-A1 | GLYCOSYLATED VALPROIC ACID ANALOGS AND USES THEREOF | Chromatin Technologies (US) | 2013-01-31 | — | — | US | disclosed |
| WO-2004046153-A1 | PRODRUG ESTERS OF CEFTRIAXONE | RANBAXY LABORATORIES LIMITED (IN) | 2004-06-03 | — | — | WO | disclosed |
| EP-0497978-B1 | CEPHALOSPORIN COMPOUNDS AND PRODUCTION THEREOF | KYOTO PHARMA IND (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5389625-A | Sweet taste; oral administering | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| US-5162573-A | Anticonvulsant, antiepileptic agent | CHIESI FARMACEUTICI S.P.A. (IT) | 1992-11-10 | — | — | US | disclosed |
| EP-0497978-A1 | CEPHALOSPORIN COMPOUNDS AND PRODUCTION THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1992-08-12 | — | — | EP | disclosed |
| EP-0250997-B1 | VALPROIC AND (E)-2-VALPROENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM | CHIESI FARMACEUTICI S.p.A. (IT) | 1992-04-15 | — | — | EP | disclosed |
| EP-0427860-A1 | NEW IMIDAZOLE DERIVATIVES, PRODUCTION THEREOF, AND USES THEREOF AS MEDICINES | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-4943567-A | EFFECTIVE AGAINST PSEUDOMONAS | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4847286-A | ANTIALLERGENS | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0293771-A2 | Cephalosporin compound and pharmaceutical composition thereof | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1988-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029924-A1 | GLYCOSYLATED VALPROIC ACID ANALOGS AND USES THEREOF | HDAC3, VGF, HDAC1 | HDAC7 9/4885HDAC8 6/4885HDAC6 10/4885 |
| US-20150119346-A1 | GLYCOSYLATED VALPROIC ACID ANALOGS AND USES THEREOF | HDAC3, VGF, HDAC1 | HDAC7 9/4885HDAC8 6/4885HDAC6 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.