Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 9/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4175716 | 0.94 | AGTR2 (0.65) | AGTR2AGTR1CYP2C9CYP2B6 | |
| SCHEMBL4183560 | 0.86 | AGTR2 (0.67) | AGTR2AGTR1CYP2C9CYP2B6 | |
| SCHEMBL4188608 | 0.81 | AGTR2 (0.66) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4194934 | 0.81 | AGTR2 (0.62) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4183014 | 0.80 | AGTR2 (0.64) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL7123178 | 0.80 | AGTR2 (0.73) | AGTR2AGTR1 | |
| SCHEMBL6823393 | 0.79 | AGTR2 (0.71) | AGTR2AGTR1 | |
| SCHEMBL17781911 | 0.78 | AGTR2 (0.66) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4188643 | 0.78 | AGTR2 (0.64) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4187910 | 0.77 | AGTR2 (0.69) | AGTR2AGTR1CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085420-A1 | BICYCLIC COMPOUNDS USEFUL AS ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2004-10-07 | — | — | WO | claimed |