Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 18/20 | 0.53 |
| ▸ | PTGDR | Q13258 | 18/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820536 | 0.88 | TBXA2R (0.42) | TBXA2RPTGDRPTGER2S1PR1 | |
| SCHEMBL12923708 | 0.86 | TBXA2R (0.41) | TBXA2RPTGDRPTGER2 | |
| SCHEMBL5420470 | 0.81 | PTGDR (0.48) | TBXA2RPTGDRPTGER2S1PR1 | |
| SCHEMBL4093843 | 0.81 | PTGDR (0.48) | TBXA2RPTGDRPTGER2S1PR1 | |
| SCHEMBL6817650 | 0.80 | S1PR1 (0.52) | TBXA2RPTGDRS1PR1 | |
| SCHEMBL5424892 | 0.78 | PTGDR (0.52) | TBXA2RPTGDRPTGER2 | |
| SCHEMBL5526809 | 0.75 | S1PR1 (0.40) | S1PR1 | |
| SCHEMBL5522526 | 0.75 | PTGDR (0.38) | TBXA2RPTGDRPTGER2S1PR1 | |
| SCHEMBL1255235 | 0.75 | PDE2A (0.50) | TBXA2RPTGDRPTGER2S1PR1 | |
| SCHEMBL1255659 | 0.72 | PDE2A (0.55) | TBXA2RPTGDRPTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305286-B1 | CYCLOPENTANOINDOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK FROSST CANADA INC (CA) | 2004-12-08 | — | — | EP | disclosed |
| EP-1305286-A2 | CYCLOPENTANOINDOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK FROSST CANADA INC. (CA) | 2003-05-02 | — | — | EP | disclosed |
| US-6410583-B1 | PROSTAGLANDIN ANTAGONIST | MERCK FROSST CANADA & CO. (CA) | 2002-06-25 | — | — | US | disclosed |
| WO-2002008186-A2 | CYCLOPENTANOINDOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK FROSST CANADA & CO. (CA) | 2002-01-31 | — | — | WO | disclosed |