Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823698 | 0.85 | TYR (0.43) | TYRMAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL6421978 | 0.77 | TYR (0.49) | TYRMAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL6919628 | 0.73 | TYR (0.46) | TYRMAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL6820551 | 0.73 | TYR (0.46) | TYRMAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL6424903 | 0.71 | TYR (0.43) | TYRMAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL14008639 | 0.69 | TYR (0.51) | TYRMAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL14008598 | 0.68 | TYR (0.50) | TYRMAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL6823700 | 0.68 | TYR (0.53) | TYRPIK3CAMTOR | |
| SCHEMBL6424333 | 0.67 | TYR (0.46) | TYRMAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL6424546 | 0.66 | TYR (0.44) | TYRMAPTTSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |