Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1597146 | 1.00 | DPP4 (0.58) | DPP4DPP7DPP8CYP2D6DPP9 | |
| SCHEMBL3601249 | 0.97 | DPP4 (0.61) | DPP4DPP7DPP8CYP2D6DPP9 | |
| SCHEMBL1598039 | 0.85 | DPP4 (0.47) | DPP4DPP7DPP8CYP2D6DPP9 | |
| SCHEMBL1598037 | 0.85 | DPP4 (0.47) | DPP4DPP7DPP8CYP2D6DPP9 | |
| SCHEMBL1598401 | 0.82 | DPP4 (0.55) | DPP4DPP7DPP8CYP2D6DPP9 | |
| SCHEMBL1598400 | 0.82 | DPP4 (0.55) | DPP4DPP7DPP8CYP2D6DPP9 | |
| SCHEMBL3934702 | 0.80 | DPP4 (0.48) | DPP4DPP7DPP8CYP2D6DPP9 | |
| SCHEMBL9075518 | 0.78 | DPP4 (0.47) | DPP4DPP7DPP8CYP2D6DPP9 | |
| SCHEMBL8695496 | 0.78 | DPP4 (0.47) | DPP4DPP7DPP8CYP2D6DPP9 | |
| SCHEMBL1597866 | 0.77 | HCRTR1 (0.54) | DPP4DPP7DPP8CYP2D6DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041807-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-05-21 | — | — | WO | disclosed |