Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 16/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821091 | 1.00 | UTS2R (0.59) | UTS2RKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6824508 | 0.92 | UTS2R (0.64) | UTS2RALDH1A1TP53FFAR4 | |
| SCHEMBL6824514 | 0.92 | UTS2R (0.64) | UTS2RALDH1A1TP53FFAR4 | |
| SCHEMBL6821152 | 0.88 | UTS2R (0.59) | UTS2R | |
| SCHEMBL6821157 | 0.88 | UTS2R (0.59) | UTS2R | |
| SCHEMBL6817433 | 0.88 | UTS2R (0.68) | UTS2RSMN1; SMN2TP53FFAR4 | |
| SCHEMBL6821074 | 0.87 | UTS2R (0.64) | UTS2RKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6821079 | 0.87 | UTS2R (0.64) | UTS2RKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6820375 | 0.85 | UTS2R (0.59) | UTS2RALDH1A1TP53LMNANPSR1 | |
| SCHEMBL6820307 | 0.85 | UTS2R (0.59) | UTS2RKDM4EMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |