Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 9/20 | 0.47 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821155 | 1.00 | NFKB1 (0.54) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL700920 | 0.85 | NFKB1 (0.56) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL1167413 | 0.85 | NFKB1 (0.56) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL6510820 | 0.85 | NFKB1 (0.74) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL5873564 | 0.85 | NFKB1 (0.74) | NFKB1MAOBP4HBABCG2MAOA | |
| Hydrochloric Acid SCHEMBL6821159 | 0.84 | NFKB1 (0.54) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL6818340 | 0.80 | MAOB (0.56) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL6818344 | 0.80 | MAOB (0.56) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL6821923 | 0.78 | HDAC1 (0.45) | NFKB1MAOBMAOALMNAMAPT | |
| SCHEMBL6821922 | 0.78 | HDAC1 (0.45) | NFKB1MAOBMAOALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |