⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1141547 | 0.83 | ELANE (0.40) | — | |
| SCHEMBL27999369 | 0.82 | ELANE (0.33) | — | |
| SCHEMBL5739290 | 0.81 | DGAT1 (0.46) | — | |
| SCHEMBL31361800 | 0.80 | ELANE (0.39) | — | |
| SCHEMBL10832757 | 0.79 | — | — | |
| SCHEMBL4676768 | 0.79 | — | — | |
| SCHEMBL11788330 | 0.79 | ELANE (0.34) | — | |
| Benzidine SCHEMBL29183444 | 0.78 | TDP1 (0.42) | — | |
| SCHEMBL30972534 | 0.78 | ELANE (0.37) | — | |
| SCHEMBL28850623 | 0.78 | ELANE (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046153-A1 | PRODRUG ESTERS OF CEFTRIAXONE | RANBAXY LABORATORIES LIMITED (IN) | 2004-06-03 | — | — | WO | claimed |
| US-4937253-A | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-26 | — | — | US | claimed |
| CN-117693509-A | Macrocyclic compounds for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2024-03-12 | — | — | CN | disclosed |
| EP-3863711-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| CN-110325523-A | Carboxylic acid aromatic amides as bradykinin B1 receptor antagonists | 拜耳制药股份公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-105646210-B | A kind of synthetic method of hydroxyl methyl trimethylacetate | 苏州艾缇克药物化学有限公司 | 2018-03-09 | — | — | CN | disclosed |
| CN-103649087-B | Substituted imidazopyridine and intermediate thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-11-30 | — | — | CN | disclosed |
| CN-103814029-B | Substituted imidazopyridazines | 拜耳知识产权有限责任公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105646210-A | Method for synthesizing methyl hydroxypivalate | 苏州艾缇克药物化学有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-103370320-B | 2,3-glyoxalidine also [1,2-c] quinoline that arylamino alcohol replaces | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-27 | — | — | CN | disclosed |
| CN-103370318-B | The Imidazopyridazine replaced | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-20 | — | — | CN | disclosed |
| CN-100408546-C | Ester compounds and theire use in forming acrylates | BATTELLE MEMORIAL INSTITUTE (US) | 2008-08-06 | — | — | CN | disclosed |
| CN-1529690-A | Ester compounds and theire use in forming acrylates | ���ض������о�Ժ | 2004-09-15 | — | — | CN | disclosed |
| EP-0907653-A1 | PROCESS FOR THE PREPARATION OF PENAM AND PENEM DERIVATIVES | ZENECA LIMITED (GB) | 1999-04-14 | — | — | EP | disclosed |
| EP-0906312-A1 | PROCESS FOR THE PREPARATION OF CARBAPENEM DERIVATIVES AND INTERMEDIATES THEREOF | ZENECA LIMITED (GB) | 1999-04-07 | — | — | EP | disclosed |
| WO-1998000429-A1 | PROCESS FOR THE PREPARATION OF PENAM AND PENEM DERIVATIVES | ZENECA LIMITED (GB) | 1998-01-08 | — | — | WO | disclosed |
| WO-1997047621-A1 | PROCESS FOR THE PREPARATION OF CARBAPENEM DERIVATIVES AND INTERMEDIATES THEREOF | ZENECA LIMITED (GB) | 1997-12-18 | — | — | WO | disclosed |
| EP-0166972-B1 | PENEM DERIVATIVES, METHODS OF PRODUCING THEM, THEIR USE AND PHARMACEUTICAL COMPOSITIONS | FARMITALIA CARLO ERBA S.r.l. (IT) | 1989-04-19 | — | — | EP | disclosed |
| US-4618606-A | Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmethyl) cephalosporins | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0055990-B1 | BETA-LACTAM ANTIBIOTICS, THEIR PREPARATION AND USE | BEECHAM GROUP PLC (GB) | 1986-06-11 | — | — | EP | disclosed |